Fri Nov 03 2023

22 articles - From Friday Oct 27 2023 to Friday Nov 03 2023

parm_toc.knit

Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multi-country meta-analysis.

Our study supports robust negative association between maternal Cu and gestational duration and positive association with risk for preterm birth. Cu concentration was strongly correlated with APRs and infection status suggesting its potential role in inflammation, a pathway implicated in the mechanisms of PTB. Therefore, maternal Cu could be used as potential marker of integrated inflammatory pathways during pregnancy and risk for preterm birth.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Children's energy intake generally increases in response to the energy density of meals but varies with the amounts and types of foods served.

Children's energy intake generally increased with greater ED; at higher-ED meals, however, energy intake decreased in a curvilinear manner without a clear breakpoint. This reduction in intake at higher ED could be explained by meal-related factors such as the portions served, rather than by sensitivity to meal energy content. Clinical trial registry numbers NCT03010501 ( (

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Dietary Medium-chain Fatty Acids and Risk of Incident Colorectal Cancer in a Predominantly Low-Income Population: A Report from the Southern Community Cohort Study.

In a predominantly low-income US population, an increased dietary C12 0 intake was associated with a substantially reduced risk of colorectal cancer only among white individuals, but not in Black individuals.

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Do global dietary nutrient datasets associate with human biomarker assessments? A regression analysis.

We find that few estimates of nutritional inadequacy from global dietary datasets associate with more direct measures of biophysical deficiency from biomarker studies. Researchers and policy makers must be cautious when applying global nutrient datasets to questions of global health and use them for limited applications.

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Effects of Wholegrain Compared to Refined Grain Intake on Cardiometabolic Risk Markers, Gut Microbiota and Gastrointestinal Symptoms in Children: A Randomized Crossover Trial.

High intake of wholegrain oats and rye reduced LDL cholesterol and TG, modulated bacterial taxa and increased beneficial metabolites in children. This supports recommendations of exchanging refined grain with wholegrain oats and rye among children. Clinicaltrials GOV NCT04430465 (Study Record | Beta ClinicalTrials.gov).

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Placental ferroportin protein abundance is associated with neonatal erythropoietic activity and iron status in newborns at high risk for iron deficiency and anemia.

Placental FPN abundance was positively associated with neonatal indicators of increased erythropoietic activity and poor iron status. The PIDI was associated with maternal and neonatal iron-related markers but in opposite directions. More data are needed from a lower-risk normative group of women to assess the generalizability of findings. Clinical trial registry These clinical trials were registered at clinicaltrials.gov as NCT01019902 ( and NCT01582802 (

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Inflamm Bowel Dis

Associations of Fish and Fish Oil Consumption With Incident Inflammatory Bowel Disease: A Population-Based Prospective Cohort Study.

Our findings indicate that oily fish and fish oil supplements might be protective factors against IBD.

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Baseline and Postinduction Intestinal Ultrasound Findings Predict Long-term Transmural and Mucosal Healing in Patients With Crohn's Disease.

Baseline and postinduction IUS findings reliably predict long-term TH and MH in patients with CD receiving infliximab.

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Exploring Predictive Biomarkers of Relapse in Ulcerative Colitis: A Proteomics Approach.

Several novel candidate tissue biomarkers have been identified in this study, which could discriminate patients with UC at risk of early relapse from those in long-term sustained remission. Our findings may pave the way for pre-emptive UC disease monitoring and therapeutic decision making.

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J Crohns Colitis

Differences in Management and Outcomes of Older and Younger Adults with Acute Severe Ulcerative Colitis.

In comparison to younger patients, older adults had lower frequency use of medical rescue therapy, higher rates of emergency surgery, and increased mortality within one year. Further research is needed to optimize care pathways in this population.

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Liver Transpl

A Modified liver donor risk index for pediatric liver transplant recipients.

Our findings indicate that there is a need to create a pediatric-specific LDRI as the Feng LDRI has not been shown to be efficacious in pediatric populations. Our index may serve as a starting point for the development of a comprehensive pediatric LDRI.

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Transplant center variability in utilizing non-standard donors and its impact on transplantation of patients with lower MELD scores.

Transplant centers that utilize more non-standard donors are more likely to successfully transplant patients at lower MELD scores. Public reporting of these data could benefit patients, caregivers, and referring providers, and be used to help maximize organ utilization.

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Pancreas

Association of Long-Term, New-Onset, and Postsurgical Diabetes With Survival in Patients With Resectable Pancreatic Cancer: A Retrospective Cohort Study.

No link was found between diabetes phenotypes and survival in resectable PDAC patients. Comprehensive prospective studies are required to validate these results.

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Comparison of Magnetic Resonance Imaging and Endoscopic Ultrasound in the Sizing of Intraductal Papillary Mucinous Neoplasia of the Pancreas.

We found a clinically relevant difference in cyst size comparing EUS and MRI. Therefore, alternating EUS and MRI for follow-up of the "worrisome feature" size growth is not reasonable.

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Metabolic Syndrome Accelerates the Age-Related Increase of Intraductal Papillary Mucinous Neoplasm of the Pancreas.

The present study suggests that the incidence of IPMN increases with age and is accelerated in the presence of MS.

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Pancreatology

Clinical features of germline BRCA½ or ATM pathogenic variant positive pancreatic cancer in Japan.

The diagnosis of gBRCA PV-positive PC has increased revealed in recent years. These tumors appear to be sensitive to platinum-based chemotherapy, with long term survival observed in gATM PV + LPV-positive patients.

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Combination of carbohydrate antigen 19-9 level and tumor size after neoadjuvant chemoradiation therapy may predict early recurrence of resectable pancreatic ductal adenocarcinoma.

A combination of a high-level carbohydrate antigen 19-9 and a T status of =T2 after neoadjuvant chemoradiotherapy are predictors of early recurrence and may be helpful for selecting patients who require a stronger preoperative treatment.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Effectiveness of Oral Tofacitinib in Chronic Pouchitis: A Prospective, Open-Label Pilot Study.

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The Rational Use of Advanced Therapies for Inflammatory Conditions of the Pouch.

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Liver Transpl

Letter to the Editor: How does Ex-vivo liver perfusion help improve the outcomes of liver transplantation in donation after cardiac death (DCD) donors?

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The prognostic implications of early-stage AKI: Defining the threshold for concern.

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Weight to go! - Glucagon-Like Peptide 1 Receptor Agonists in Liver Transplant Recipients.

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Letters&Replies

Letters to the editors and authors’ replies